Richard Boxer, MD, FACS, practicing physician and entrepreneur, explains the devastating flaws in Teladoc’s business model which has never made a profit (as opposed to UpScript which has been profitable by combining telemedicine with prescription delivery), and how the lessons from Innovating in Health Care influenced some of the cost-cutting businesses he founded including Urology Specialists, a firm that cut the costs of clinical research by partnering with physician offices and iAnthus, a medical cannabis company that uses vertical integration and technology to control production costs.